Mukherjee, A. K. ; Ghosal, S. K. ; Maity, C. R. (1997) Lysosomal membrane stabilization by α-tocopherol against the damaging action of Vipera russelli venom phospholipase A2 Cellular and Molecular Life Sciences, 53 (2). pp. 152-155. ISSN 1420-682X
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Official URL: http://doi.org/10.1007/pl00000586
Related URL: http://dx.doi.org/10.1007/pl00000586
Abstract
This investigation shows the membrane stabilizing effect of α-tocopherol against the damaging action of viper venom phospholipase A2 (PLA2). Liver lysosomal membranes from rats fed 100 mg and 200 mg α-tocopherol acetate per kilogram of diet were more resistant to damage by viper venom PLA2 compared with vitamin E-deficient rats. The membrane stabilizing effect of vitamin E is proposed to be due to the formation of a complex with the phospholipid hydrolysis products of the membrane.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer Nature |
| Keywords: | Vitamin E; phospholipase A2; membrane stabilization |
| ID Code: | 126920 |
| Deposited On: | 13 Oct 2022 08:50 |
| Last Modified: | 13 Oct 2022 08:50 |
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