Makarova, Ya. V. ; Shelukhina, I. V. ; Mukherjee, A. K. ; Kuznetsov, D. V. ; Tsetlin, V. I. ; Utkin, Yu. N. (2017) Detection of human neuronal α7 nicotinic acetylcholine receptors by conjugates of snake α-neurotoxin with quantum dots Doklady Biochemistry and Biophysics, 475 (1). pp. 253-255. ISSN 1607-6729
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Official URL: http://doi.org/10.1134/S1607672917040032
Related URL: http://dx.doi.org/10.1134/S1607672917040032
Abstract
Fluorescent derivatives are widely used to study the structure and functions of proteins. Quantum dots (QDs), fluorescent semiconductor nanocrystals, have a high quantum yield and are much more resistant to bleaching compared to organic dyes. Conjugates of α-neurotoxins with QDs were used for visualization of human α7 acetylcholine receptors heterologously expressed in GH4C1 pituitary adenoma cells. Specific staining of cells by the conjugated toxins was observed.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer Nature |
| ID Code: | 126797 |
| Deposited On: | 13 Oct 2022 07:01 |
| Last Modified: | 13 Oct 2022 07:01 |
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