Dash, Jyotirmayee ; Dhara, Kalyan ; Kapat, Ajoy ; Ghosh, Tridev (2016) Transition-Metal-Free Terminal Alkyne Addition to Isatins Synthesis, 48 (23). pp. 4260-4268. ISSN 0039-7881
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Official URL: http://doi.org/10.1055/s-0035-1562611
Related URL: http://dx.doi.org/10.1055/s-0035-1562611
Abstract
A ‘direct’ alkynylation of isatins, which uses potassium tert-butoxide to provide the desired 3-hydroxy-3-ethynyl-2-oxindoles in good to high yields, is reported. This protocol proceeds smoothly for both electron-rich and electron-deficient alkynes in comparable reaction rates and does not require any specially design ligand or expensive transition-metal catalysts.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to ResearchGate GmbH. |
| ID Code: | 126593 |
| Deposited On: | 17 Oct 2022 05:45 |
| Last Modified: | 17 Oct 2022 05:45 |
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