A New and Flexible Synthesis of 4-Hydroxypyridines: Rapid Access to Caerulomycins A, E and Functionalized Terpyridines

Dash, Jyotirmayee ; Reissig, Hans-Ulrich (2009) A New and Flexible Synthesis of 4-Hydroxypyridines: Rapid Access to Caerulomycins A, E and Functionalized Terpyridines Chemistry - A European Journal, 15 (28). pp. 6811-6814. ISSN 0947-6539

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Official URL: http://doi.org/10.1002/chem.200900939

Related URL: http://dx.doi.org/10.1002/chem.200900939

Abstract

Simple, but yet unknown: 1,3-Diketones, ammonia, and carboxylic acids are the precursors for the efficient synthesis of 4-hydroxypyridines and the corresponding nonaflate derivatives. This provides simple and practical access to a variety of highly substituted pyridine derivatives, including antibiotic natural products such as caerulomycins A, E and functionalized terpyridines (see scheme).

Item Type:Article
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ID Code:126540
Deposited On:17 Oct 2022 05:50
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