Baidya, Mithu ; Dwivedi, Hemlata ; Shukla, Arun K (2017) Frozen in action: cryo-EM structure of a GPCR–G-protein complex Nature Structural & Molecular Biology, 24 (6). pp. 500-502. ISSN 1545-9993
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Official URL: http://doi.org/10.1038/nsmb.3418
Related URL: http://dx.doi.org/10.1038/nsmb.3418
Abstract
Interaction with heterotrimeric G proteins is a hallmark of G-protein-coupled receptor (GPCR) family members, and it is the key step for a diverse range of cell-signaling cascades. A recent cryo-EM structure of the human calcitonin receptor (CTR) in complex with a G-protein heterotrimer reveals novel insights into receptor–G-protein coupling.
| Item Type: | Article |
|---|---|
| ID Code: | 126440 |
| Deposited On: | 13 Oct 2022 06:04 |
| Last Modified: | 13 Oct 2022 06:04 |
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