Woodruff, Trent M. ; Shukla, Arun K. (2020) The Complement C5a-C5aR1 GPCR Axis in COVID-19 Therapeutics Trends in Immunology, 41 (11). pp. 965-967. ISSN 14714906
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Official URL: http://doi.org/10.1016/j.it.2020.09.008
Related URL: http://dx.doi.org/10.1016/j.it.2020.09.008
Abstract
The current pandemic of coronavirus disease (COVID-19) caused by SARS-CoV-2 is a significant global health challenge. A recent study by Carvelli and colleagues now demonstrates the involvement of complement C5a and its receptor C5aR1 in disease progression and suggests that blockade of the C5a-C5aR1 axis may represent a potential therapeutic strategy against COVID-19.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Ltd. |
| Keywords: | COVID-19; GPCRs; SARS-CoV-2; cellular signaling; complement system; drug discovery |
| ID Code: | 126356 |
| Deposited On: | 13 Oct 2022 05:57 |
| Last Modified: | 13 Oct 2022 05:57 |
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