Ravikumar, Gayatri ; Crasta, Julian ; Prabhu, Jyothi S. ; Thomas, Tinku ; Dwarkanath, Pratibha ; Thomas, Annamma ; Kurpad, Anura V. ; Sridhar, Tirumalai Srinivas (2019) CD15 as a marker of fetoplacental endothelial immaturity in IUGR placentas The Journal of Maternal-Fetal & Neonatal Medicine, 32 (10). pp. 1646-1653. ISSN 1476-7058
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Official URL: http://doi.org/10.1080/14767058.2017.1414179
Related URL: http://dx.doi.org/10.1080/14767058.2017.1414179
Abstract
Structural or functional defects in the placenta, are the primary cause of growth restriction of the fetus. Morphological examination of such placentas from intrauterine growth restricted (IUGR) fetuses often appears deceptively normal. Evaluation of angiogenesis and fetoplacental vasculature is critical to understand the underlying pathogenesis of fetal growth restriction in both idiopathic as well as cases where it is thought to be secondary to complications like preeclampsia (PE). We analyzed the immaturity of fetoplacental vasculature using CD15, which is a stage specific embryonic antigen known to be expressed in immature endothelium.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Informa UK Limited |
| Keywords: | Chronic hypoxia; fetoplacental endothelial immaturity; gestational age; preeclampsia |
| ID Code: | 126287 |
| Deposited On: | 13 Oct 2022 05:46 |
| Last Modified: | 13 Oct 2022 05:46 |
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