Mane, Shivshankar R. ; Rao N, Vijayakameswara ; Chatterjee, Koushik ; Dinda, Himadri ; Nag, Soma ; Kishore, Abhinoy ; Sarma, Jayasri Das ; Shunmugam, Raja (2012) A unique polymeric nano-carrier for anti-tuberculosis therapy Journal of Materials Chemistry, 22 (37). p. 19639. ISSN 0959-9428
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Official URL: http://doi.org/10.1039/c2jm33860b
Related URL: http://dx.doi.org/10.1039/c2jm33860b
Abstract
A nano-carrier made of a norbornene derived isoniazid copolymer is designed. In vitro cytotoxicity assay and renal clearance analysis clearly indicate that the newly designed nano-carrier is biocompatible in nature. This nano-carrier with a hydrazone linker is shown to be a promising reservoir with excellent performance for an efficient drug delivery system. Moreover, the system also offers an effective strategy and new modalities for the development of TB therapy.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry. |
| ID Code: | 126283 |
| Deposited On: | 22 Sep 2022 11:52 |
| Last Modified: | 19 Oct 2022 10:21 |
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