Mane, Shivshankar R. ; Rao N, Vijayakameswara ; Chaterjee, Koushik ; Dinda, Himadri ; Nag, Soma ; Kishore, Abhinoy ; Das Sarma, Jayasri ; Shunmugam, Raja (2012) Amphiphilic Homopolymer Vesicles as Unique Nano-Carriers for Cancer Therapy Macromolecules, 45 (19). pp. 8037-8042. ISSN 0024-9297
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Official URL: http://doi.org/10.1021/ma301644m
Related URL: http://dx.doi.org/10.1021/ma301644m
Abstract
A unique polymersome from amphiphilic, norbornene-derived thiobarbiturate homopolymers (NDTH) and its application as nanocarrier for cancer therapy are elaborately discussed. Various experiments like structural characterizations, control studies, cell viability studies, encapsulation studies, and MTT assay against 4T cancer cells are performed on these NDTH polymersomes to substantiate our claims. All of these results demonstrate that these self-assembled NDTH vesicles have great scope in the world of medicine, and they also symbolize promising carriers for the stimuli-triggered intracellular delivery of hydrophobic drugs.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to ResearchGate GmbH. |
| ID Code: | 126279 |
| Deposited On: | 17 Oct 2022 06:18 |
| Last Modified: | 19 Oct 2022 11:54 |
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