Does early vitamin B12supplementation improve neurodevelopment and cognitive function in childhood and into school age: a study protocol for extended follow-ups from randomised controlled trials in India and Tanzania

Winje, Brita Askeland ; Kvestad, Ingrid ; Krishnamachari, Srinivasan ; Manji, Karim ; Taneja, Sunita ; Bellinger, David C ; Bhandari, Nita ; Bisht, Shruti ; Darling, Anne Marie ; Duggan, Christopher P ; Fawzi, Wafaie ; Hysing, Mari ; Kumar, Tivendra ; Kurpad, Anura V ; Sudfeld, Christopher R ; Svensen, Erling ; Thomas, Susan ; Strand, Tor A (2018) Does early vitamin B12supplementation improve neurodevelopment and cognitive function in childhood and into school age: a study protocol for extended follow-ups from randomised controlled trials in India and Tanzania BMJ Open, 8 (2). e018962. ISSN 2044-6055

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Official URL: http://doi.org/10.1136/bmjopen-2017-018962

Related URL: http://dx.doi.org/10.1136/bmjopen-2017-018962

Abstract

As many as 250 million children under the age of 5 may not be reaching their full developmental potential partly due to poor nutrition during pregnancy and the first 2 years of life. Micronutrients, including vitamin B12, are important for the development of brain structure and function; however, the timing, duration and severity of deficiencies may alter the impact on functional development outcomes. Consequently, to fully explore the effect of vitamin B12 on cognitive function, it is crucial to measure neurodevelopment at different ages, in different populations and with vitamin B12 supplementation at different times during the critical periods of neurodevelopment.

Item Type:	Article
Source:	Copyright of this article belongs to BMJ Publishing Group Ltd
ID Code:	126275
Deposited On:	13 Oct 2022 05:46
Last Modified:	13 Oct 2022 05:46

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