N, Vijayakameswara Rao ; Dinda, Himadri ; Ganivada, Mutyala Naidu ; Das Sarma, Jayasri ; Shunmugam, Raja (2014) Efficient approach to prepare multiple chemotherapeutic agent conjugated nanocarrier Chem. Commun., 50 (88). pp. 13540-13543. ISSN 1359-7345
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Official URL: http://doi.org/10.1039/c4cc04445b
Related URL: http://dx.doi.org/10.1039/c4cc04445b
Abstract
A pH-responsive, multiple chemotherapeutic agent derived nanocarrier has been synthesized by conjugating doxorubicin, indomethacin, and folate to the backbone of norbornene polymer. Drug molecules are connected to the norbornene backbone by an ester linker to demonstrate the pH-responsive capabilities. The complete chemical and biological properties of the new norbornene-based polymeric nanocarrier, intended for combination cancer chemotherapy, are discussed.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry |
| ID Code: | 126269 |
| Deposited On: | 22 Sep 2022 11:18 |
| Last Modified: | 19 Oct 2022 10:13 |
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