Tryptophan oxidation in young children with environmental enteric dysfunction classified by the lactulose rhamnose ratio

Shivakumar, Nirupama ; Hsu, Jean W ; Kashyap, Sindhu ; Thomas, Tinku ; Kurpad, Anura V ; Jahoor, Farook (2022) Tryptophan oxidation in young children with environmental enteric dysfunction classified by the lactulose rhamnose ratio The American Journal of Clinical Nutrition . ISSN 0002-9165

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Official URL: http://doi.org/10.1093/ajcn/nqac171

Related URL: http://dx.doi.org/10.1093/ajcn/nqac171

Abstract

In young children, associations between linear growth faltering, environmental enteric dysfunction (EED), and the plasma kynurenine (Kyn)/tryptophan (Trp) ratio (KTR) have led to the proposal that higher Trp catabolism in response to intestinal/systemic inflammation limits Trp availability for protein synthesis, resulting in impaired growth.

Item Type:Article
Source:Copyright of this article belongs to American Society for Nutrition
Keywords:environmental enteric dysfunction, children, lactulose rhamnose ratio, kynurenine tryptophan ratio, tryptophan oxidation, tryptophan flux
ID Code:126145
Deposited On:13 Oct 2022 05:40
Last Modified:13 Oct 2022 05:40

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