Microbe-assisted biodegradation, bioremediation and metabolic engineering

Abstract

We summarize here the recent research and development in the area of microbe assisted biodegradation and remediation processes by different research lab in the country. The various substituted hydrocarbons as pollutants have been studied by different groups. The depth of the study includes the characterization of key bacterial metabolic pathway for target pollutants through both genome and proteome levels. By understanding the pathway, in few cases the metabolic engineering approached have been demonstrated for the efficient utilization of pollutants. The better understanding to key enzyme were explored using protein modeling or by understanding its expression through heterologous host. The review also presents few case studies where pilot scale demonstration of contaminated sites with selected pollutants, have also been carried out effectively.