Paul, Amrita ; Biswas, Angana ; Sinha, Sreyashi ; Shah, Sk. Sheriff ; Bera, Manoranjan ; Mandal, Mahitosh ; Singh, N. D. Pradeep (2019) Push–Pull Stilbene: Visible Light Activated Photoremovable Protecting Group for Alcohols and Carboxylic Acids with Fluorescence Reporting Employed for Drug Delivery Organic Letters, 21 (9). pp. 2968-2972. ISSN 1523-7060
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Official URL: http://doi.org/10.1021/acs.orglett.9b00124
Related URL: http://dx.doi.org/10.1021/acs.orglett.9b00124
Abstract
For the first time we have utilized push–pull stilbene as a visible light activated photoremovable protecting group (PRPG) for the uncaging of alcohols and carboxylic acids. The PRPG efficiently release caged molecules with good photochemical quantum yield. It is capable of monitoring the release in real time owing to its fluorescence “turn on” phenomenon upon photorelease in polar medium. The efficient photorelease and real time monitoring abilities of push–pull stilbene were employed for in vitro drug delivery.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 124068 |
| Deposited On: | 02 Nov 2021 07:05 |
| Last Modified: | 02 Nov 2021 07:05 |
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