Samanta, Debabrata ; Roy, Syamantak ; Sasmal, Ranjan ; Saha, Nilanjana Das ; K R, Pradeep ; Viswanatha, Ranjani ; Agasti, Sarit S. ; Maji, Tapas Kumar (2019) Solvent Adaptive Dynamic Metal‐Organic Soft Hybrid for Imaging and Biological Delivery Angewandte Chemie International Edition, 58 (15). pp. 5008-5012. ISSN 1433-7851
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Official URL: http://doi.org/10.1002/anie.201900692
Related URL: http://dx.doi.org/10.1002/anie.201900692
Abstract
A solvent adaptive nanoscale MOF (NMOF) with dynamic morphology was devised based on an asymmetric bola-amphiphilic oligo-(p-phenyleneethynylene) (OPE) dicarboxylate linker. The emissive and non-toxic NMOF is cell permeable and allowed live-cell imaging. Cisplatin (14.4 wt %) and doxorubicin (4.1 wt %) were encapsulated in the polar cavity of the NMOF and delivered to HeLa cells with micromolar cytotoxicity.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley & Sons, Inc. |
| ID Code: | 124016 |
| Deposited On: | 29 Oct 2021 09:35 |
| Last Modified: | 29 Oct 2021 09:35 |
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