Aggarwal, Abhishek ; Naskar, Supriyo ; Sahoo, Anil Kumar ; Mogurampelly, Santosh ; Garai, Ashok ; Maiti, Prabal K (2020) What do we know about DNA mechanics so far? Current Opinion in Structural Biology, 64 . pp. 42-50. ISSN 0959-440X
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Official URL: http://doi.org/10.1016/j.sbi.2020.05.010
Related URL: http://dx.doi.org/10.1016/j.sbi.2020.05.010
Abstract
The DNA molecule, apart from carrying the genetic information, plays a crucial role in a variety of biological processes and finds applications in drug design, nanotechnology and nanoelectronics. The molecule undergoes significant structural transitions under the influence of forces due to physiological and non-physiological environments. Here, we summarize the insights gained from simulations and single-molecule experiments on the structural transitions and mechanics of DNA under force, as well as its elastic properties, in various environmental conditions, and discuss appealing future directions.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 123938 |
| Deposited On: | 25 Oct 2021 11:52 |
| Last Modified: | 25 Oct 2021 11:52 |
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