Balraju, V. ; Dev, R. Vasu ; Reddy, D. Srinivasa ; Iqbal, Javed (2006) Synthesis of cyclic peptides using a palladium-catalyzed enyne cycloisomerization Tetrahedron Letters, 47 (21). pp. 3569-3571. ISSN 0040-4039
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Official URL: http://doi.org/10.1016/j.tetlet.2006.03.053
Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.03.053
Abstract
In this letter, we report a palladium-catalyzed enyne cycloisomerization of linear peptides to generate small cyclic peptides embedded with a conjugated 1,3-diene. The utility of these resulting macrocyclic dienes is demonstrated by carrying out [4+2] cycloadditions with dienophiles to generate constrained cyclic peptides with cyclic linkers.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier B.V. |
| ID Code: | 122016 |
| Deposited On: | 27 Jul 2021 09:50 |
| Last Modified: | 30 Jul 2021 12:49 |
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