An efficient synthesis of varenicline

Pasikanti, Srinivas ; Srinivasa Reddy, D. ; Venkatesham, B. ; Dubey, P.K. ; Iqbal, Javed ; Das, Parthasarathi (2010) An efficient synthesis of varenicline Tetrahedron Letters, 51 (1). pp. 151-152. ISSN 0040-4039

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Official URL: http://doi.org/10.1016/j.tetlet.2009.10.107

Related URL: http://dx.doi.org/10.1016/j.tetlet.2009.10.107

Abstract

Synthesis of varenicline the antismoking drug has been achieved in six steps with 10% overall yield. A Diels–Alder reaction, oxidative cleavage of an olefin and reductive amination remain as key steps in the synthesis

Item Type:Article
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ID Code:122011
Deposited On:27 Jul 2021 09:22
Last Modified:30 Jul 2021 12:44

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