Kurhade, Suresh E. ; Mengawade, Tanaji ; Bhuniya, Debnath ; Palle, Venkata P. ; Reddy, D. Srinivasa (2011) Synthesis of novel sugar-lactam conjugates using the Aubé reaction Organic and Biomolecular Chemistry, 9 (3). pp. 744-747. ISSN 1477-0520
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Official URL: http://doi.org/10.1039/C0OB00719F
Related URL: http://dx.doi.org/10.1039/C0OB00719F
Abstract
An efficient and convenient method for the synthesis of sugar-lactam conjugates is reported starting from readily available sugar azides using the Aubé reaction. Cyclic azido alcohols are used in the Aubé reaction for the first time in a carbohydrate setting. The resulting glycoconjugates could be further used to increase the chemical diversity on the sugar backbone, and may find potential applications as glycomimetics, peptidomimetics, in glycotargeting and in CNS drug delivery.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to The Royal Society of Chemistry |
| ID Code: | 122008 |
| Deposited On: | 27 Jul 2021 09:10 |
| Last Modified: | 27 Jul 2021 09:10 |
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