Synthesis of Molluscicidal Agent Cyanolide A Macrolactone fromd-(−)-Pantolactone

Hajare, Atul K. ; Ravikumar, Velayutham ; Khaleel, Shaik ; Bhuniya, Debnath ; Reddy, D. Srinivasa (2011) Synthesis of Molluscicidal Agent Cyanolide A Macrolactone fromd-(−)-Pantolactone Journal of Organic Chemistry, 76 (3). pp. 963-966. ISSN 0022-3263

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Official URL: http://doi.org/10.1021/jo101782q

Related URL: http://dx.doi.org/10.1021/jo101782q

Abstract

An efficient synthesis of potent molluscicidal agent cyanolide A, a glycosidic 16-membered macrolide, starting from D-(-)-pantolactone is reported. Highly stereoselective aldol, oxa-Michael addition, and Yamaguchi macrolactonization are the key steps in the present synthesis.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society
ID Code:122007
Deposited On:27 Jul 2021 09:08
Last Modified:27 Jul 2021 09:08

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