Synthesis of revised structure of klaivanolide (acetylmelodorinol)

Muthyala, Ramaiah ; Raut, Gajanan N. ; Wagh, Sachin B. ; Reddy, D. Srinivasa (2015) Synthesis of revised structure of klaivanolide (acetylmelodorinol) Arkivoc, 2016 (2). pp. 116-122. ISSN 1551-7012

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Official URL: http://doi.org/10.3998/ark.5550190.p009.231

Related URL: http://dx.doi.org/10.3998/ark.5550190.p009.231

Abstract

Klaivanolide (acetylmelodorinol) is an anti-leishmanial/anti-trypanosomal agent isolated from Uvaria klaineana and the structure was originally assigned as a 7-membered lactone with extended conjugation and S-configuration at the lactone junction. Very recently, the structure of klaivanolide was revised as previously known compound acetylmelodorinol. Now, we have synthesized the revised structure in racemic form using a short route.

Item Type:Article
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Deposited On:23 Jul 2021 09:12
Last Modified:23 Jul 2021 09:12

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