Histological evolution of caecal lesions in experimental amoebiasis

Gill, N. J. ; Ganguly, N. K. ; Mahajan, R. C. ; Bhushnurmath, S. R. ; Dilawari, J. B. (1984) Histological evolution of caecal lesions in experimental amoebiasis Transactions of the Royal Society of Tropical Medicine and Hygiene, 78 (5). pp. 631-638. ISSN 0035-9203

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/003592...

Related URL: http://dx.doi.org/10.1016/0035-9203(84)90225-6

Abstract

Histopathological studies in guinea-pigs infected intracaecally with Entamoeba histolytica were carried out longitudinally on days 3, 7, 11, 15, 20 and 35 after infection. Three characteristic modes of development of caecal lesions were observed. These in order of their prevalence were the classical inflammatory cellular infiltration, lymphoid hypertrophy and necrotizing colitis. Occasional amoeboma formation was observed in progesterone-treated animals. This is the first time that histological lesions which mimic the human intestinal amoebiasis have been described in the experimental animal.

Item Type:Article
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ID Code:12189
Deposited On:10 Nov 2010 04:28
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