Synthesis of benzo-fused medium ring cyclic ethers via a Michael addition–ring closing metathesis strategy involving nitroaliphatic compounds

Deb, Indubhusan ; John, Sumod ; Namboothiri, Irishi N.N. (2007) Synthesis of benzo-fused medium ring cyclic ethers via a Michael addition–ring closing metathesis strategy involving nitroaliphatic compounds Tetrahedron, 63 (48). pp. 11991-11997. ISSN 0040-4020

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Official URL: http://doi.org/10.1016/j.tet.2007.09.009

Related URL: http://dx.doi.org/10.1016/j.tet.2007.09.009

Abstract

Nitroalkenes derived from O-protected salicylaldehyde undergo facile Michael-type addition of nucleophiles possessing unsaturated tether. Ring closing metathesis of the Michael adducts provides benzo-fused medium ring cyclic ethers possessing a nitroalkyl functionality.

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