Rajesh, Kunjanpillai ; Shanbhag, Pramod ; Raghavendra, Manjoji ; Bhardwaj, Pallavi ; Namboothiri, Irishi N.N. (2010) One-pot three component α-aminoalkylation of conjugated nitroalkenes and nitrodienes Tetrahedron Letters, 51 (5). pp. 846-849. ISSN 0040-4039
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Official URL: http://doi.org/10.1016/j.tetlet.2009.12.015
Related URL: http://dx.doi.org/10.1016/j.tetlet.2009.12.015
Abstract
Nitroethylenes possessing aryl, heteroaryl, and alkyl substituents at the β-position as well as δ-substituted nitrobutadienes undergo facile aminoalkylation at the α-position upon treatment with formaldehyde and a secondary amine in the presence of imidazole and trifluoroacetic acid to afford α-aminoalkylated nitroalkenes and nitrodienes in good to excellent yield and stereoselectivity.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 121573 |
| Deposited On: | 19 Jul 2021 10:07 |
| Last Modified: | 19 Jul 2021 10:07 |
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