Kumar, Rahul ; Verma, Deepti ; Mobin, Shaikh M. ; Namboothiri, Irishi N. N. (2012) One-Pot, Two-Step Conversion of Aldehydes to Phosphonyl- and Sulfonylpyrazoles Using Bestmann–Ohira Reagent Organic Letters, 14 (16). pp. 4070-4073. ISSN 1523-7060
Full text not available from this repository.
Official URL: http://doi.org/10.1021/ol301695e
Related URL: http://dx.doi.org/10.1021/ol301695e
Abstract
A one-pot, two-step, three-component method for the conversion of commercially available aldehydes to phosphonylpyrazoles has been developed, demonstrating, for the first time, the dual reactivity of the Bestmann-Ohira reagent (BOR) in a single-pot transformation. This method, extended to the synthesis of sulfonylpyrazoles by employing BOR in the first step and a diazomethyl sulfone in the second step, is complementary, with regard to regioselectivity, to the previous methods for the synthesis of such functionalized pyrazoles.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 121566 |
| Deposited On: | 19 Jul 2021 09:12 |
| Last Modified: | 19 Jul 2021 09:12 |
Repository Staff Only: item control page
