Chauhan, A. ; Dilawari, J. B. ; Chawla, Y. K. ; Jameel, S. ; Kaur, U. ; Ganguly, N. K. (1993) Hepatitis E virus transmission to a volunteer Lancet, 341 (8838). pp. 149-150. ISSN 0099-5355
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/014067...
Related URL: http://dx.doi.org/10.1016/0140-6736(93)90008-5
Abstract
Hepatitis E virus (HEV) causes an enteric non-A, non-B hepatitis. The disease occurs in epidemic settings and sporadically, and viral transmission is thought to be faecal-oral. We present here a single volunteer study of HEV transmission followed by disease. Clinical and biochemical features of the infection correlated with H EV detection in the stools and sera by reverse transcription/polymerase chain amplification. IgG antibody has persisted for 2 years. The presence of HEV in serum before clinical signs appeared suggests that in endemic areas sporadic transmission of HEV may also occur parenterally.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Lancet. |
| ID Code: | 12141 |
| Deposited On: | 10 Nov 2010 04:17 |
| Last Modified: | 11 Jul 2012 10:28 |
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