Jardim, Guilherme A. M. ; Guimarães, Tiago T. ; Pinto, Maria do Carmo F. R. ; Cavalcanti, Bruno C. ; de Farias, Kaio M. ; Pessoa, Claudia ; Gatto, Claudia C. ; Nair, Divya K. ; Namboothiri, Irishi N. N. ; da Silva Júnior, Eufrânio N. (2015) Naphthoquinone-based chalcone hybrids and derivatives: synthesis and potent activity against cancer cell lines MedChemComm, 6 (1). pp. 120-130. ISSN 2040-2503
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Official URL: http://doi.org/10.1039/c4md00371c
Related URL: http://dx.doi.org/10.1039/c4md00371c
Abstract
Novel naphthoquinone-based chalcones were prepared from the reaction between 3-bromo-nor-β-lapachone and amino-chalcones. Lapachone derivatives are also described here. All the substances were evaluated against cancer and normal cell lines and several compounds demonstrated potent antitumor activity.
Item Type: | Article |
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Source: | Copyright of this article belongs to The Royal Society of Chemistry. |
ID Code: | 121338 |
Deposited On: | 14 Jul 2021 11:41 |
Last Modified: | 14 Jul 2021 11:41 |
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