Ramachary, Dhevalapally B. ; Narayana, Vidadala V. ; Prasad, M. Shiva ; Ramakumar, Kinthada (2009) High-yielding synthesis of Nefopam analogues (functionalized benzoxazocines) by sequential one-pot cascade operations Organic and Biomolecular Chemistry, 7 (17). p. 3372. ISSN 1477-0520
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Official URL: http://doi.org/10.1039/B910397J
Related URL: http://dx.doi.org/10.1039/B910397J
Abstract
An efficient amine-/ruthenium-catalyzed three-step process for the synthesis of Nefopam analogues was achieved through combinations of cascade enamine amination/iso-aromatization/allylation and diene or enyne metathesis as key steps starting from functionalized Hagemann's esters. In this communication, we discovered the application of ruthenium-catalysis on olefins containing free amines without in situ formation of salts.
Item Type: | Article |
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Source: | Copyright of this article belongs to The Royal Society of Chemistry. |
ID Code: | 120772 |
Deposited On: | 05 Jul 2021 06:29 |
Last Modified: | 05 Jul 2021 06:29 |
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