Rapid two-step synthesis of drug-like polycyclic substances by sequential multi-catalysis cascade reactions

Ramachary, Dhevalapally B. ; Mondal, Rumpa ; Venkaiah, Chintalapudi (2010) Rapid two-step synthesis of drug-like polycyclic substances by sequential multi-catalysis cascade reactions Organic and Biomolecular Chemistry, 8 (2). pp. 321-325. ISSN 1477-0520

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Official URL: http://doi.org/10.1039/B920152A

Related URL: http://dx.doi.org/10.1039/B920152A

Abstract

An efficient amino acid-/self-/base-/ruthenium-/thermal-catalyzed two-step process for the synthesis of functionalized drug-like carbocycles was achieved through combinations of cascade TCRA/C-allylation/enyne-RCM/Diels–Alder reactions as key steps starting from simple acyclic substrates. In this communication, we report the two-step synthesis of drug-like carbocycles through a combination of organocatalysis with ruthenium-catalysis.

Item Type:Article
Source:Copyright of this article belongs to The Royal Society of Chemistry.
ID Code:120763
Deposited On:05 Jul 2021 05:29
Last Modified:05 Jul 2021 05:29

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