Azide–acetonitrile “click” reaction triggered by Cs2CO3: the atom-economic, high-yielding synthesis of 5-amino-1,2,3-triazoles

Krishna, Patoju M. ; Ramachary, Dhevalapally B. ; Peesapati, Sruthi (2015) Azide–acetonitrile “click” reaction triggered by Cs2CO3: the atom-economic, high-yielding synthesis of 5-amino-1,2,3-triazoles RSC Advances, 5 (76). pp. 62062-62066. ISSN 2046-2069

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Official URL: http://doi.org/10.1039/C5RA12308A

Related URL: http://dx.doi.org/10.1039/C5RA12308A

Abstract

Medicinally important 5-amino-1,2,3-triazoles were synthesized using a novel Cs2CO3-catalyzed azide–acetonitrile[3 + 2]-cycloaddition. Aryl azides and aryl acetonitriles were employed in this transformation resulting in excellent yields with high regioselectivity.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:120661
Deposited On:03 Jul 2021 07:05
Last Modified:03 Jul 2021 07:05

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