An Aldehyde‐Azomethine Imine [3+2]‐Cycloaddition: High‐Yielding Regioselective Synthesis of Substituted N,N ‐Bicyclic Pyrazolidinones

Gujral, Jagjeet ; Reddy, T. Prabhakar ; Gorachand, B. ; Ramachary, Dhevalapally B. (2018) An Aldehyde‐Azomethine Imine [3+2]‐Cycloaddition: High‐Yielding Regioselective Synthesis of Substituted N,N ‐Bicyclic Pyrazolidinones ChemistrySelect, 3 (27). pp. 7900-7905. ISSN 2365-6549

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Official URL: http://doi.org/10.1002/slct.201801328

Related URL: http://dx.doi.org/10.1002/slct.201801328

Abstract

An enolate mediated aldehyde-azomethine imine [3+2] cycloaddition of various aldehydes with N,N-cyclic azomethine imines is reported under DBU or tBuOK-catalysis. High reaction rate, ease of operation, simple catalyst, easily accessible starting materials and a wide substrate scope with numerous applications make this reaction an ideal addition to the click chemistry.

Item Type:Article
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ID Code:120641
Deposited On:03 Jul 2021 05:18
Last Modified:03 Jul 2021 05:18

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