Cherian, Sarah ; Potdar, Varsha ; Jadhav, Santosh ; Yadav, Pragya ; Gupta, Nivedita ; Das, Mousmi ; Rakshit, Partha ; Singh, Sujeet ; Abraham, Priya ; Panda, Samiran ; NIC team, . (2021) Convergent evolution of SARS-CoV-2 spike mutations, L452R, E484Q and P681R, in the second wave of COVID-19 in Maharashtra, India bioRxiv .
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Official URL: http://doi.org/10.1101/2021.04.22.440932
Related URL: http://dx.doi.org/10.1101/2021.04.22.440932
Abstract
As the global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic expands, genomic epidemiology and whole genome sequencing are being constantly used to investigate its transmissions and evolution. In the backdrop of the global emergence of “variants of concern” (VOCs) during December 2020 and an upsurge in a state in the western part of India since January 2021, whole genome sequencing and analysis of spike protein mutations using sequence and structural approaches was undertaken to identify possible new variants and gauge the fitness of current circulating strains.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Cold Spring Harbor Laboratory Press. |
| ID Code: | 120493 |
| Deposited On: | 30 Jun 2021 10:26 |
| Last Modified: | 30 Jun 2021 10:26 |
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