Nagaraju, Anugula ; Ramulu, B. Janaki ; Shukla, Gaurav ; Srivastava, Abhijeet ; Verma, Girijesh Kumar ; Raghuvanshi, Keshav ; Singh, Maya Shankar (2014) A facile and straightforward synthesis of 1,2,3-thiadiazoles from α-enolicdithioesters via nitrosation/reduction/diazotization/cyclization cascade in one-pot Tetrahedron Letters, 55 (15). pp. 2430-2433. ISSN 0040-4039
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Official URL: http://doi.org/10.1016/j.tetlet.2014.02.115
Related URL: http://dx.doi.org/10.1016/j.tetlet.2014.02.115
Abstract
An operationally simple, economical, and straightforward synthesis of diverse 4,5-disubstituted 1,2,3-thiadiazoles from α-enolicdithioesters has been achieved via nitrosation/reduction/diazotization/cyclization sequence in one-pot through the formation of cascade 1–2 (N–S) and 3–4 (C–N) bonds. Importantly, this is the first straightforward entry to highly functionalized 1,2,3-thiadiazoles from dithioesters.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
Keywords: | α-Enolicdithioesters; Diazotization; Cascade Annulation; 1,2,3-Thiadiazoles; One-Pot. |
ID Code: | 120250 |
Deposited On: | 24 Jun 2021 11:03 |
Last Modified: | 24 Jun 2021 11:03 |
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