Pathigoolla, Atchutarao ; Sureshan, Kana M. (2016) The topochemical synthesis of triazole-linked homobasic DNA Chemical Communications, 52 (5). pp. 886-888. ISSN 1359-7345
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Official URL: http://doi.org/10.1039/C5CC08834H
Related URL: http://dx.doi.org/10.1039/C5CC08834H
Abstract
Triazolyl-DNA (TLDNA), a DNA-analog wherein phosphodiester units are replaced by triazole motifs, is of great interest. We have synthesized TLDNA oligomers by adopting the Topochemical Azide–Alkyne Cycloaddition (TAAC) reaction. A nucleoside decorated with the azide and alkyne units crystallized with the proximal placement of the azide and alkyne units of the adjacent molecules and underwent the TAAC reaction to form TLDNA oligomers.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Royal Society of Chemistry. |
| ID Code: | 119899 |
| Deposited On: | 18 Jun 2021 06:57 |
| Last Modified: | 18 Jun 2021 06:57 |
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