Yadav, Divya ; Ballal, Sanjana ; Yadav, Madhav Prasad ; Tripathi, Madhavi ; Roesch, Frank ; Bal, Chandrasekhar (2020) Evaluation of [68Ga]Ga-DATA-TOC for imaging of neuroendocrine tumours: comparison with [68Ga]Ga-DOTA-NOC PET/CT European Journal of Nuclear Medicine and Molecular Imaging, 47 (4). pp. 860-869. ISSN 1619-7070
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Official URL: http://doi.org/10.1007/s00259-019-04611-1
Related URL: http://dx.doi.org/10.1007/s00259-019-04611-1
Abstract
Recently, the new hybrid chelator DATA (6-amino-1,4-diazepine-triacetate) has been introduced, which has the advantage of high yield and radiolabelling of DATA-based octreotide derivative (TOC) at room temperature in contrast to tetraazacyclododecane-1,4,7,10-tetraacetate (DOTA) that needs 95 °C for effective labelling. However, the diagnostic potential of DATA-TOC has not been studied with other chelators in humans. The aim of this study was to compare the diagnostic efficacy of [68Ga]Ga-DATA-TOC with [68Ga]Ga-DOTA-NOC (which is the current standard for imaging neuroendocrine tumours (NET)) in patients of gastroenteropancreatic neuroendocrine tumours (GEP-NETs).
Item Type: | Article |
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Source: | Copyright of this article belongs to Springer-Verlag. |
ID Code: | 119858 |
Deposited On: | 17 Jun 2021 12:58 |
Last Modified: | 17 Jun 2021 12:58 |
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