Evaluation of [68Ga]Ga-DATA-TOC for imaging of neuroendocrine tumours: comparison with [68Ga]Ga-DOTA-NOC PET/CT

Yadav, Divya ; Ballal, Sanjana ; Yadav, Madhav Prasad ; Tripathi, Madhavi ; Roesch, Frank ; Bal, Chandrasekhar (2020) Evaluation of [68Ga]Ga-DATA-TOC for imaging of neuroendocrine tumours: comparison with [68Ga]Ga-DOTA-NOC PET/CT European Journal of Nuclear Medicine and Molecular Imaging, 47 (4). pp. 860-869. ISSN 1619-7070

Full text not available from this repository.

Official URL: http://doi.org/10.1007/s00259-019-04611-1

Related URL: http://dx.doi.org/10.1007/s00259-019-04611-1

Abstract

Recently, the new hybrid chelator DATA (6-amino-1,4-diazepine-triacetate) has been introduced, which has the advantage of high yield and radiolabelling of DATA-based octreotide derivative (TOC) at room temperature in contrast to tetraazacyclododecane-1,4,7,10-tetraacetate (DOTA) that needs 95 °C for effective labelling. However, the diagnostic potential of DATA-TOC has not been studied with other chelators in humans. The aim of this study was to compare the diagnostic efficacy of [68Ga]Ga-DATA-TOC with [68Ga]Ga-DOTA-NOC (which is the current standard for imaging neuroendocrine tumours (NET)) in patients of gastroenteropancreatic neuroendocrine tumours (GEP-NETs).

Item Type:Article
Source:Copyright of this article belongs to Springer-Verlag.
ID Code:119858
Deposited On:17 Jun 2021 12:58
Last Modified:17 Jun 2021 12:58

Repository Staff Only: item control page