Biodistribution, pharmacokinetics, dosimetry of [68Ga]Ga-DOTA.SA.FAPi, and the head-to-head comparison with [18F]F-FDG PET/CT in patients with various cancers

Ballal, Sanjana ; Yadav, Madhav Prasad ; Moon, Euy Sung ; Kramer, Vasko S. ; Roesch, Frank ; Kumari, Samta ; Tripathi, Madhavi ; ArunRaj, Sreedharan Thankarajan ; Sarswat, Sulochana ; Bal, Chandrasekhar (2021) Biodistribution, pharmacokinetics, dosimetry of [68Ga]Ga-DOTA.SA.FAPi, and the head-to-head comparison with [18F]F-FDG PET/CT in patients with various cancers European Journal of Nuclear Medicine and Molecular Imaging, 48 (6). pp. 1915-1931. ISSN 1619-7070

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Official URL: http://doi.org/10.1007/s00259-020-05132-y

Related URL: http://dx.doi.org/10.1007/s00259-020-05132-y

Abstract

[68Ga]Ga-labeled fibroblast activation protein inhibitors ([68Ga]Ga-FAPi) have shown promising preclinical and clinical results in PET imaging. The present study aimed to evaluate the biodistribution, pharmacokinetics, and dosimetry of [68Ga]Ga-DOTA.SA.FAPi, another modified FAPi tracer, and performed a head-to-head comparison with [18F]F-FDG PET/CT scans in patients with various cancers.

Item Type:Article
Source:Copyright of this article belongs to Springer-Verlag.
ID Code:119848
Deposited On:17 Jun 2021 12:39
Last Modified:17 Jun 2021 12:47

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