Synthesis of Novel Heterocycles from Benzoin-α-oxime by Reaction with Electrophile­s

Singh, M. S. ; Singh, A. K. (2004) Synthesis of Novel Heterocycles from Benzoin-α-oxime by Reaction with Electrophile­s Synthesis (6). pp. 837-839. ISSN 0039-7881

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Official URL: http://doi.org/10.1055/s-2004-815999

Related URL: http://dx.doi.org/10.1055/s-2004-815999

Abstract

A useful sequence of reactions for the synthesis of a variety of heterocyclic systems is described. The reaction of benzoina-oxime (2-hydroxy-1,2-diphenyl-1-ethanone oxime) with sodium hydride in propan-2-ol produces a 1,5-dianion. The cyclization of this dianion with dielectrophiles affords dioxazines, dioxazepines, dioxazocine, dioxazonine and dioxazaphosphines in good yields

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