Nandi, Ganesh C. ; Singh, Maya S. ; Ila, Hiriyakkanavar ; Junjappa, Hiriyakkanavar (2011) Highly Regioselective One-Pot, Three-Component Synthesis of 1-Aryl-3,4-Substituted/Annulated-5-(Cycloamino)/(Alkylamino)pyrazoles from β-Oxodithioesters European Journal of Organic Chemistry, 2012 (5). pp. 967-974. ISSN 1434-193X
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Official URL: http://doi.org/10.1002/ejoc.201101397
Related URL: http://dx.doi.org/10.1002/ejoc.201101397
Abstract
A highly regioselective synthesis of the title compounds by one-pot, three-component cyclocondensation of β-oxodithioester, amine, and hydrazine in ethanol at reflux in the presence of a catalytic amount of acetic acid is reported. Densely functionalized pyrazoles were efficiently constructed through the cyclization of a thioamide intermediate that was generated in situ from the β-oxodithioester.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| ID Code: | 119654 |
| Deposited On: | 15 Jun 2021 13:27 |
| Last Modified: | 15 Jun 2021 13:27 |
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