Venkatasubramanian, G. ; Latha, V. ; Gangadhar, B. N. ; Janakiramaiah, N. ; Subbakrishna, D. K. ; Jayakumar, P. N. ; Keshavan, M. S. (2003) Neurological soft signs in never-treated schizophrenia Acta Psychiatrica Scandinavica, 108 (2). pp. 144-146. ISSN 0001-690X
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Official URL: http://doi.org/10.1034/j.1600-0447.2003.00113.x
Related URL: http://dx.doi.org/10.1034/j.1600-0447.2003.00113.x
Abstract
Objective: Studies of Neurological Soft Signs (NSS) in schizophrenia are confounded by handedness, inconsistent methodology, and prior treatment with neuroleptics. The study objective is to examine NSS in never-treated schizophrenia. Method: We examined the NSS in treatment-naïve schizophrenia patients (n = 21) and age, sex, education, and handedness matched normal controls (n = 21) using the modified Neurological Evaluation Scale with good inter-rater reliability. Results: Schizophrenia patients had significantly more NSS than normals. No significant correlation was found between illness duration and NSS. Conclusion: Higher neurological signs in never-treated patients and their lack of association with illness duration suggest neurodevelopmental etiopathogenesis of schizophrenia.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley & Sons, Inc. |
| Keywords: | Neurological Soft Signs; Never-Treated Schizophrenia. |
| ID Code: | 119173 |
| Deposited On: | 08 Jun 2021 11:58 |
| Last Modified: | 08 Jun 2021 11:58 |
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