Jayakumar, Peruvamba N. ; Venkatasubramanian, Ganesan ; Gangadhar, Bangalore N. ; Janakiramaiah, Nimmagadda ; Keshavan, Matcheri S. (2005) Optimized voxel-based morphometry of gray matter volume in first-episode, antipsychotic-naïve schizophrenia Progress in Neuro-Psychopharmacology and Biological Psychiatry, 29 (4). pp. 587-591. ISSN 0278-5846
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Official URL: http://doi.org/10.1016/j.pnpbp.2005.01.020
Related URL: http://dx.doi.org/10.1016/j.pnpbp.2005.01.020
Abstract
This study examined gray matter (GM) volume abnormalities in first-episode, antipsychotic-naïve Indian schizophrenia patients. Magnetic resonance images of 18 schizophrenia patients and 18 matched healthy comparison subjects were analyzed by optimized voxel-based morphometry. Schizophrenia patients had significantly smaller global GM and greater global CSF volumes and smaller regional GM volume in superior frontal, inferior frontal, cingulate, post-central, superior temporal and parahippocampal gyri, inferior parietal lobule, insula, caudate nuclei, thalamus and cerebellum. Findings suggest limbic, heteromodal cortical, striatal, thalamic and cerebellar abnormalities in schizophrenia.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Inc. |
| Keywords: | Antipsychotic-Naïve; Schizophrenia; Voxel-Based Morphometry. |
| ID Code: | 119167 |
| Deposited On: | 08 Jun 2021 11:42 |
| Last Modified: | 08 Jun 2021 11:42 |
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