Proulx, Éliane ; Suri, Deepika ; Heximer, Scott P. ; Vaidya, Vidita A. ; Lambe, Evelyn K. (2014) Early Stress Prevents the Potentiation of Muscarinic Excitation by Calcium Release in Adult Prefrontal Cortex Biological Psychiatry, 76 (4). pp. 315-323. ISSN 0006-3223
Full text not available from this repository.
Official URL: http://doi.org/10.1016/j.biopsych.2013.10.017
Related URL: http://dx.doi.org/10.1016/j.biopsych.2013.10.017
Abstract
The experience of early stress contributes to the etiology of several psychiatric disorders and can lead to lasting deficits in working memory and attention. These executive functions require activation of the prefrontal cortex (PFC) by muscarinic M1 acetylcholine (ACh) receptors. Such Gαq-protein coupled receptors trigger the release of calcium (Ca2+) from internal stores and elicit prolonged neuronal excitation.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Society of Biological Psychiatry. |
| ID Code: | 119037 |
| Deposited On: | 07 Jun 2021 07:39 |
| Last Modified: | 07 Jun 2021 07:39 |
Repository Staff Only: item control page
