Venkatasubramanian, Ganesan ; Arasappa, Rashmi ; Christopher, Rita ; Gangadhar, Bangalore N. (2010) Neuropharmacology of schizophrenia: is there a role for leptin? Clinical Chemistry and Laboratory Medicine, 48 (6). ISSN 1434-6621
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Official URL: http://doi.org/10.1515/CCLM.2010.158
Related URL: http://dx.doi.org/10.1515/CCLM.2010.158
Abstract
A significant relationship between beneficial therapeutic effects and antipsychotic-induced weight gain has been demonstrated in various studies for various medications including clozapine, olanzapine and risperido new summarized in (1)x.Of interest, leptin has been postulated as a potential mediator underlying this intriguing link between weight gain and better clinical outcome (1). In this letter, we describe for the first time a significant positive correlation between base line serum leptin concentrations and improvements in positive symptoms in patients with schizophrenia following antipsychotic treatment.
Item Type: | Article |
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Source: | Copyright of this article belongs to Walter de Gruyter GmbH. |
Keywords: | Leptin; Schizophrenia. |
ID Code: | 118842 |
Deposited On: | 30 May 2021 07:44 |
Last Modified: | 30 May 2021 07:44 |
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