Banerji, Shantanu ; Ande, Sudharsana Rao ; Maddika, Subbareddy ; Banerji, Versha ; Rashedi, Iran ; Owens, Neil W. ; Zuse, Anne ; Schweizer, Frank ; Los, Marek (2008) Peptides and Peptidomimetics as Cancer Therapy Sensitizing Agents In: Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy. Part of the Cancer Drug Discovery and Development book series (CDD&D) . Springer Nature Switzerland AG, pp. 279-303. ISBN 978-1-59745-474-2
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Official URL: http://doi.org/10.1007/978-1-59745-474-2_17
Related URL: http://dx.doi.org/10.1007/978-1-59745-474-2_17
Abstract
Apoptosis, or programmed cell death, is the body's normal method of disposing of unwanted or damaged cells, and represents a crucial step in the life cycle of a cell [1]. Disruption of this process is believed to be associated with tumor growth and resistance to chemotherapy, and so has recently become a major focus of research [2]. While the process is still not completely understood, apoptosis is mediated through a cascade of events induced from extracellular or intracellular signals [3] and converge to induce the activity of a group of enzymes, specifically the caspases, which dismantle the cell once activated.
| Item Type: | Book Section |
|---|---|
| Source: | Copyright of this article belongs to Springer Nature. |
| ID Code: | 118576 |
| Deposited On: | 25 May 2021 12:48 |
| Last Modified: | 25 May 2021 12:48 |
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