A new type of biocompatible fluorescent probe AFN for fixed and live cell imaging of intracellular lipid droplets

Sharma, Ashutosh ; Umar, Shahida ; Kar, Parmita ; Singh, Kavita ; Sachdev, Monika ; Goel, Atul (2016) A new type of biocompatible fluorescent probe AFN for fixed and live cell imaging of intracellular lipid droplets Analyst, 141 (1). pp. 137-143. ISSN 0003-2654

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Official URL: http://doi.org/10.1039/C5AN01623A

Related URL: http://dx.doi.org/10.1039/C5AN01623A

Abstract

We discovered a new class of nontoxic, highly fluorogenic and biocompatible probe AFN for selective staining of intracellular Lipid Droplets (LDs) in both fixed and live human cervical cancer cells (HeLa) and 3T3-L1 pre-adipocytes without any background artifacts. The salient features of the probe are its visible excitation maximum, aqueous compatibility, selectivity and remarkable stability (for more than a week) in live cells, even better than commercially available Nile red.

Item Type:Article
Source:Copyright of this article belongs to The Royal Society of Chemistry.
ID Code:117965
Deposited On:07 May 2021 08:39
Last Modified:07 May 2021 08:39

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