Goel, Atul ; Sharma, Ashutosh ; Kathuria, Manoj ; Bhattacharjee, Arindam ; Verma, Ashwni ; Mishra, Prabhat R. ; Nazir, Aamir ; Mitra, Kalyan (2014) New Fluoranthene FLUN-550 as a Fluorescent Probe for Selective Staining and Quantification of Intracellular Lipid Droplets Organic Letters, 16 (3). pp. 756-759. ISSN 1523-7060
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Official URL: http://doi.org/10.1021/ol403470d
Related URL: http://dx.doi.org/10.1021/ol403470d
Abstract
A new class of live cell permeant, nontoxic fluoranthene-based fluorescent probe (FLUN-550) having a high Stokes shift in aqueous medium has been discovered. It showed selective staining of lipid droplets (LDs, dynamic cytoplasmic organelles) at a low concentration without background noise in in vitro live cell imaging of 3T3-L1 preadipocytes, J774 macrophages, MCF7 breast cancer cells, and single-celled, parasitic protozoa Leishmania donovani promastigotes and in vivo nonparasitic soil nematode C. elegans.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Chemical Society. |
| ID Code: | 117958 |
| Deposited On: | 07 May 2021 07:23 |
| Last Modified: | 07 May 2021 07:23 |
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