Singh, Fateh V. ; Chaurasia, Sumit ; Joshi, Maya D. ; Srivastava, Arvind K. ; Goel, Atul (2007) Synthesis and in vivo antihyperglycemic activity of nature-mimicking furanyl-2-pyranones in STZ-S model Bioorganic & Medicinal Chemistry Letters, 17 (9). pp. 2425-2429. ISSN 0960-894X
Full text not available from this repository.
Official URL: http://doi.org/10.1016/j.bmcl.2007.02.036
Related URL: http://dx.doi.org/10.1016/j.bmcl.2007.02.036
Abstract
Various nature-mimicking pyranones such as 6-(2,5-dimethylfuran-3-yl)-pyran-2-one and 6-(furan-2-yl)-pyran-2-one derivatives were synthesized and evaluated for their in vivo antihyperglycemic activity in sucrose-loaded streptozotocin-induced diabetic rat model. Five of the test compounds showed significant lowering of plasma glucose level in STZ-S model.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Furanyl-2-pyranones; Synthesis; Antihyperglycemic; STZ-S Model; Antidiabetic. |
| ID Code: | 117925 |
| Deposited On: | 06 May 2021 09:11 |
| Last Modified: | 06 May 2021 09:11 |
Repository Staff Only: item control page
