Amberlyst 15-Catalyzed Efficient Synthesis of 5-Acetyl-4-hydroxy-coumarone and 5-Acetyl-6-hydroxy-coumarone: Crucial Precursors for Several Naturally Occurring Furanoflavones

Goel, Atul ; Dixit, Manish (2004) Amberlyst 15-Catalyzed Efficient Synthesis of 5-Acetyl-4-hydroxy-coumarone and 5-Acetyl-6-hydroxy-coumarone: Crucial Precursors for Several Naturally Occurring Furanoflavones Synlett, 2004 (11). pp. 1990-1994. ISSN 0936-5214

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Official URL: http://doi.org/10.1055/S-2004-831180

Related URL: http://dx.doi.org/10.1055/S-2004-831180

Abstract

A novel approach to the total synthesis of naturally occurring furanoflavones and furanochalcones is described. Angular and linear furanoflavones and furanochalcones have been prepared in just four steps, using economical reagents and simple reaction conditions. The key step of our approach is the formation of crucial precursors, 5-acetyl-4-hydroxy-coumarone and 5-acetyl-6-hydroxy-coumarone by Amberlyst 15-catalyzed cyclization of phen­oxyacetal.

Item Type:Article
Source:Copyright of this article belongs to Georg Thieme Verlag.
Keywords:Furanoflavone; Furanochalcone; Lanceolatin B; Isopongaglabol; Glabone; Pongone; Pongamol; Ovalitenone.
ID Code:117905
Deposited On:06 May 2021 07:23
Last Modified:06 May 2021 07:23

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