Synthesis of Aminonicotinonitriles and Diaminopyridines through Base-Catalyzed Ring Transformation of 2H-Pyran-2-ones†

Farhanullah, . ; Agarwal, Nidhi ; Goel, Atul ; Ram, Vishnu Ji (2003) Synthesis of Aminonicotinonitriles and Diaminopyridines through Base-Catalyzed Ring Transformation of 2H-Pyran-2-ones† Journal of Organic Chemistry, 68 (7). pp. 2983-2985. ISSN 0022-3263

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Official URL: http://doi.org/10.1021/jo0204496

Related URL: http://dx.doi.org/10.1021/jo0204496

Abstract

An efficient and convenient synthesis of 2-amino-6-aryl-4-methylsulfanylnicotinonitriles (2), 2-amino-6-aryl-4-substituted-aminonicotinonitriles (4), and 2-amino-6-aryl-4-substituted-aminopyridines (6) has been delineated and illustrated through base-catalyzed ring transformation of 6-aryl-3-cyano-4-methylsulfanyl/substituted-amino-2H-pyran-2-ones (1, 3, and 5) with cyanamide and ammonium carbonate separately.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:117898
Deposited On:06 May 2021 06:20
Last Modified:06 May 2021 06:20

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