5-Cyano-2-thiouracils and their derivatives: a new class of leishmanicides

Ram, Vishnu Ji ; Goel, Atul ; Nath, Mahedra ; Srivastava, Pratibha (1994) 5-Cyano-2-thiouracils and their derivatives: a new class of leishmanicides Bioorganic & Medicinal Chemistry Letters, 4 (22). pp. 2653-2656. ISSN 0960-894X

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Official URL: http://doi.org/10.1016/S0960-894X(01)80690-9

Related URL: http://dx.doi.org/10.1016/S0960-894X(01)80690-9

Abstract

Several 5-Cyano-6-substituted-2-thiouracils (1a–e) and their monocyclic (2,3,4,6) and bicyclic (5) derivatives have been prepared and evaluated for in vivo leishmanicidal activity against L. donovani in hamster. Thiouracils and its derivatives are synthesized as potent leishmanicides.

Item Type:Article
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ID Code:117877
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