Sequential Occurrence of Preneoplastic Lesions and Accumulation of Loss of Heterozygosity in Patients With Gallbladder Stones Suggest Causal Association With Gallbladder Cancer

Jain, Kajal ; Mohapatra, Trilochan ; Das, Prasenjit ; Misra, Mahesh Chandra ; Gupta, Siddhartha Datta ; Ghosh, Manju ; Kabra, Madhulika ; Bansal, Virinder Kumar ; Kumar, Subodh ; Sreenivas, Vishnubhatla ; Garg, Pramod Kumar (2014) Sequential Occurrence of Preneoplastic Lesions and Accumulation of Loss of Heterozygosity in Patients With Gallbladder Stones Suggest Causal Association With Gallbladder Cancer Annals of Surgery, 260 (6). pp. 1073-1080. ISSN 0003-4932

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Official URL: http://doi.org/10.1097/SLA.0000000000000495

Related URL: http://dx.doi.org/10.1097/SLA.0000000000000495

Abstract

Background: Causal association of gallbladder stones with gallbladder cancer (GBC) is not yet well established. Objective: To study the frequency of occurrence of preneoplastic histological lesions and loss of heterozygosity (LOH) of tumor suppressor genes in patients with gallstones.

Item Type:Article
Source:Copyright of this article belongs to Wolters Kluwer Health, Inc.
ID Code:117810
Deposited On:04 May 2021 06:13
Last Modified:04 May 2021 06:13

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